Syphilis is a sexually transmitted infection caused by the spirochete bacterium. The signs and symptoms of syphilis vary but may include a single chancre (skin ulceration), a diffuse rash which frequently involves the palms of the hands and soles of the feet. Latent syphilis with little to no symptoms followed by tertiary syphilis with gummas, neurological, or cardiac symptoms. Syphilis is thought to have infected 12 million additional people worldwide in 1999, with greater than 90% of cases in the developing world.
Infection Risk=High | Health Consequences = High